As stated in our website, the Clinical Academic Center – Braga (2CA-Braga) is a non-profit partnership between the University of Minho and the Hospital de Braga, with a focus on research, clinical care, education and training. Our vision is to create a paradigm shift for healthcare: a larger number of subjects can be appropriately monitored and healthcare providers can proactively engage their population into an adjustable healthcare mode. Strengthening this vision, the 2CA-BRAGA seeks to ensure that medical research breakthroughs lead to direct clinical benefits for patients. This Newsletter gives you an overview of the clinical research centre activities along with a snapshot of some planned actions for 2016. We hope you enjoy the reading!